This Week in Virology TWiV 1164: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin informs us about the World Health Organization research and development plan to combat endemic pathogens including hepatitis C virus, RSV and dengue virus, another case of mpox in Britian, the Marburg virus outbreak in Rwanda, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if there is a benefit to additional COVID vaccinations after the initial series, ISDA guideline for using anti-SARS-CoV-2 monoclonal antibody therapy for prophylaxis, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, if and how do severe secondary bacterial infections develop following SARS-CoV-2 infection, and if COVID-19 associates with a risk of autoimmune and autoinflammatory connective tissue disorders.
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Links for this episode- Is the WHO the world’s NIH: endemic pathogens initiative (eBioMedicine)
- Another two cases of mpox in Britian (Reuters)
- How to stop Marburg virus (Rwanda Biomedical Centre)
- Marburg Virus fact sheet (Rwanda Biomedical Centre)
- Influenza weekly surveillance report: cliff notes (CDC FluView)
- RSV NETwork (CDC RSV)
- Respiratory virus activity (CDC Respiratory Illnesses)
- COVID-19 deaths (CDC)
- COVID-19 national and regional trends (CDC)
- Waste water scan for 11 pathogens (WastewaterSCan)
- COVID-19 variant tracker (CDC)
- SARS-CoV-2 genomes galore (Nextstrain)
- Symptom reduction after additional vaccine dose during Omicron (OFID)
- IDSA Guideline update for SARS-CoV-2 monoclonal antibody pemivibart pre-exposure prophylaxis (CID)
- Where to get pemgarda (Pemgarda)
- EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
- Fusion center near you….if in NY (Prime Fusions)
- CDC Quarantine guidelines (CDC)
- NIH COVID-19 treatment guidelines (NIH)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Drug interaction checker (University of Liverpool)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- What to do when sick with a respiratory virus (CDC)
- When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids, dexamethasone at the right time (OFID)
- Anticoagulation guidelines (hematology.org)
- Secondary bacterial infection follows COVID-19 (Nature Communications)
- Daniel Griffin’s evidence-based medical practices for long COVID (OFID)
- Autoimmune and autoinflammatory connective tissue disorders following COVID-19 (JAMA Dermatology)
- Letters read on TWiV 1164
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv