182: Innovating Continuous Bioprocessing with Vibrating Membrane Filtration with Jarno Robin - Part 2

What if the secret to making continuous bioprocessing practical, sustainable, and far simpler has been shaking - literally - just beneath our feet?

For years, the industry has grappled with the complexities of continuous manufacturing, with technologies like ATF (alternating tangential flow) steadily dominating the perfusion landscape. But what if there's a game-changer right around the corner - a technology that vibrates membranes, not workflows, promising both higher performance and a greener footprint?

Enter Jarno Robin, a pioneering force in membrane filtration and Pharma Business Development Director at Sani Membranes. With two decades of experience implementing ATF and championing continuous innovation in bioprocessing, Jarno isn’t just speculating about change—he’s building it. In this episode, host David Brühlmann gets hands-on with Jarno as they unpack Sani’s patented Vibro Membrane Filtration (VMF) technology and its bold promise to transform upstream and downstream bioprocessing.

Here are three reasons you can’t afford to miss this conversation:

• Vibration Over Crossflow: Sani’s VMF system shakes up conventional wisdom by using vibration to generate turbulence, achieving uniform transmembrane pressure, reducing cell damage, and enabling robust, scalable separations across applications from mAbs to cultivated meat and even challenging mRNA workflows.
• Seamless Tech Swap (and Sustainability): Transitioning from ATF or TFF to VMF? Jarno explains how the setup is surprisingly straightforward, requires fewer connections at scale, dramatically cuts chemical use, and can slash your environmental footprint, as membranes last years instead of months.
• Innovation Demands Resilience: Beyond equipment specs, Jarno pulls back the curtain on what it really takes to drive innovation in pharma: relentless belief, hours of extra work, and the patience to let good data - and internal advocates - build momentum for change.

Ready to see bioprocessing through a new lens? Tune in to discover how vibrating membranes may help you simplify your CMC development pipeline, reduce waste, and position your organization for a more continuous, efficient future.

Connect with Jarno Robin:

LinkedIn: www.linkedin.com/in/jarno-robin

Website: www.sanimembranes.com

Curious about continuous processing challenges and breakthroughs? Don’t miss these previous episodes.

• Episodes 39-40: Balancing Perfusion Process Development and Sustainability with Jochen Sieck
• Episodes 85-86: Bioprocess 4.0: Integrated Continuous Biomanufacturing with Massimo Morbidelli
• Episodes 153-154: The Future of Bioprocessing: Industry 4.0, Digital Twins, and Continuous Manufacturing Strategies with Tiago Matos

Next step:

Book a free consultation to help you get started on any questions you may have about bioprocess development: https://bruehlmann-consulting.com/call

🧬 Ready to eliminate CMC chaos and hit your IND timeline with absolute certainty? Get the complete Notion CMC Dashboard at https://stan.store/SmartBiotech/p/cmc-dashboard-for-biotech-founders - the proven roadmap that's guided successful mAb programs to

🧬 Stop second-guessing your CMC strategy before investor meetings. Our 1-Week CMC Assessment reveals your roadmap gaps and transforms uncertain founders into confident presenters who ace investor meetings. Secure your assessment at https://stan.store/SmartBiotech/p/get-cmc-clarity-in-1-week--investor-ready

Support the show