BMJ Best Practice Podcast

Hyperthyroidism

Jul 29, 2024
Dr. Salman Razvi, a Consultant Endocrinologist and Senior Lecturer at Queen Elizabeth Hospital, delves into hyperthyroidism, primarily focusing on Graves' disease. He highlights the global prevalence and serious complications like heart failure. The discussion covers symptoms, diagnosis, and the nuances of treating hyperthyroidism, especially in pregnancy. Razvi also addresses the challenges of weight management post-treatment and the impact of hereditary factors and lifestyle choices on the condition.
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INSIGHT

Basics of Hyperthyroidism

  • Hyperthyroidism occurs when the thyroid gland produces excess hormones beyond the body's need.
  • It is typically indicated by high thyroid hormones and low TSH levels in blood tests.
ADVICE

Diagnosing Causes of Hyperthyroidism

  • After confirming hyperthyroidism, measure TSH receptor antibodies (TRAB) to diagnose Graves' disease.
  • Use imaging tests only if TRAB is negative to identify other causes like toxic nodular goiter.
INSIGHT

Thyroiditis as a Hyperthyroidism Cause

  • Thyroiditis causes overactive thyroid by inflammation that releases preformed hormones, often self-limiting.
  • Causes include viral infections, some medications, and iodine from radiology contrast agents.
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