The Resus Room July 2025; papers of the month
4 snips
Jul 1, 2025 This discussion dives into a systematic review comparing noradrenaline and adrenaline for post-cardiac arrest care, revealing some intriguing insights. They also tackle a groundbreaking trial on using ketamine with midazolam for pediatric seizures, showing impressive results in seizure termination. Finally, they assess the efficacy of intramuscular versus intravenous metoclopramide for migraines, highlighting its potential to reduce emergency department stays. Each topic promises to challenge and refine current medical practices!
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Noradrenaline Lowers Rearrest Risk
- Noradrenaline use post-cardiac arrest is linked to lower risk of recurrent arrest than adrenaline.
- Yet survival and good neurological outcome differences are not statistically significant.
Ketamine Boosts Pediatric Seizure Control
- Adding ketamine to midazolam greatly increases seizure cessation in pediatric status epilepticus.
- Ketamine's benefit is especially notable when seizures last longer than 30 minutes upon hospital arrival.
IM Metoclopramide Speeds Migraine Care
- Use IM metoclopramide for clear-cut migraine patients to reduce emergency length of stay.
- Reserve IV route for unclear or complicated headaches needing investigations and cannulation.