High Intensity Health with Mike Mutzel, MS
Insulin Resistance Fuels Artery-Clogging Plaque, Early Atherosclerosis
May 25, 2024
Discover how insulin resistance in the heart is linked to early atherosclerosis and heart issues, with insights on glucose uptake, metabolic syndrome, and cardiovascular risk factors. Learn about the impact of cardiac metabolism on heart health and the importance of metabolic flexibility in reducing the risk of heart failure.
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Quick takeaways
- Insulin resistance in the heart worsens atherosclerosis and cardiovascular risk, emphasizing the crucial link between metabolic health and heart function.
- The heart's ability to utilize different energy sources affects cardiovascular health, highlighting the significance of metabolic flexibility in preventing heart-related complications.
Deep dives
Impact of Insulin Resistance on Atherosclerosis
Insulin resistance within the heart exacerbates atherosclerosis, contributing significantly to cardiovascular disease burden. A study focusing on fluorodeoxyglucose uptake highlighted reduced glucose uptake in insulin-resistant individuals, correlating strongly with the atherosclerotic process over time. This study, the first if its kind, followed 800 subjects over five years, demonstrating the critical link between insulin resistance and cardiovascular risk factors in the development of atherosclerosis.
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