Stuff You Missed in History Class

SYMHC Classics: Rabies

Aug 30, 2025
Delve into the intriguing history and modern significance of rabies. Discover how a tragic disease led to groundbreaking vaccinations that have saved countless lives. Explore cultural perceptions and notable outbreaks throughout history, from ancient writings to recent fox bites. Learn about the pivotal research by Gaultier and Pasteur that transformed rabies from folklore to a medically recognized threat. This narrative emphasizes the importance of awareness, education, and global efforts in combating this deadly disease.
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ANECDOTE

Dog Rabies Reached Americas With Colonists

  • European colonization introduced dog rabies to the Americas, where before the virus mostly infected bats and skunks.
  • Dog rabies spread more widely after colonists brought infected animals on shorter voyages and established dense dog populations.
INSIGHT

Rabies Is Preventable With Timely Prophylaxis

  • Rabies is almost always fatal once symptoms appear, but modern prophylaxis is nearly 100% effective at preventing death after exposure.
  • The vaccine is one of the most effective medical interventions we have against a deadly virus.
INSIGHT

Attenuation Led To Post-Exposure Vaccination

  • Pasteur attenuated rabies virus by air-drying infected rabbit spinal cords to weaken the virus.
  • Exposing animals to the attenuated material produced resistance, inspiring post-exposure vaccination ideas.
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