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Biotech 2050 Podcast

Revolutionizing CAR T with CRISPR: Rachel Haurwitz, President & CEO of Caribou Biosciences

Mar 11, 2025
Rachel Haurwitz, the President & CEO of Caribou Biosciences, dives into the future of CRISPR and CAR T therapies. As a pioneer in genome editing, she discusses the transformative potential of off-the-shelf CAR T solutions, currently being tested in multiple clinical trials. Rachel reflects on her journey from co-founding the company at just 26, the importance of strategic partnerships, and navigating the biotech landscape. She also emphasizes the need for diversity and the evolving dynamics in biotech entrepreneurship.
26:25

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Podcast summary created with Snipd AI

Quick takeaways

  • Rachel Haurwitz highlights the evolution and necessity of off-the-shelf CAR T therapies to improve patient accessibility and affordability.
  • The discussion emphasizes the critical role of strategic funding and partnerships in navigating the unpredictable biotech landscape for startups.

Deep dives

Rachel Horwitz's Journey in Biotech

Rachel Horwitz, the president and CEO of Caribou Biosciences, shares her unique path in the biotech field, beginning with her pivotal role in CRISPR research in the mid-2000s. As the first student in Jennifer Doudna's lab, she was part of the early investigation into CRISPR technology when it was still a nascent concept. Her passion for translating academic discoveries into practical solutions led her to co-found Caribou, where she focuses on developing innovative genome editing technologies. This journey exemplifies the transition from theoretical science to impactful biotechnological applications, highlighting the importance of academic research in driving industry advancements.

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