Covid-19 Special - Tucker Goodrich

Tucker Goodrich is a Wall Street tech guru and citizen scientist who healed his own illnesses mainly by cutting out vegetable oils and gluten from his diet. He's been on the podcast twice before.

We talk about:

• Imperial College model (no tree grows to heaven)
• Diamond Princess
• John Ionnaidis paper
• Tucker’s post for Italy data
• ARDS soybean oil paper
• SARS cell change post infection - increases metabolism of w6 fats
• Serum w6 means more ARDS
• Malcolm Kendrick

Some references:

"COVID-19: Is Italy — and Mass Quarantine — "Flattening the Curve" or Riding the Trend?"

http://yelling-stop.blogspot.com/2020/04/covid-19-is-italy-and-mass-quarantine.html

1.

Plurad D, Green D, Inaba K, Belzberg H, Demetriades D, Rhee P. A 6-year review of total parenteral nutrition use and association with late-onset acute respiratory distress syndrome among ventilated trauma victims. Injury. 2009;40(5):511-515. doi:10.1016/j.injury.2008.07.025

"The incidence of late ARDS among those exposed to TPN was 28.7% (116/404) compared with 3.9% (76/1942) among those not so exposed. Adjustments for potential confounding associated risk factors were made."

"For instance, metabolism of omega-3 fatty acids leads to less inflammation than metabolism of omega-6 fatty acids and may reduce the harmful side effects of TPN"

2.

Quinlan GJ, Lamb NJ, Evans TW, Gutteridge JMC. Plasma fatty acid changes and increased lipid peroxidation in patients with adult respiratory distress syndrome. Read Online: Critical Care Medicine | Society of Critical Care Medicine. 1996;24(2):241–246. https://journals.lww.com/ccmjournal/Abstract/1996/02000/Plasma_fatty_acid_changes_and_increased_lipid.10.aspx. Accessed April 5, 2020.

"As plasma linoleic acid concentrations decreased, there was usually an increase in plasma 4-hydroxy-2-nonenal values, one of its specific peroxidation products, suggestive of severe oxidative stress leading to molecular damage to lipids."

3.

Bursten SL, Federighi DA, Parsons PE, et al. An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome. Read Online: Critical Care Medicine | Society of Critical Care Medicine. 1996;24(7):1129–1136. doi:10.1097/00003246-199607000-00011

"Increases in unsaturated serum acyl chain ratios differentiate between healthy and seriously ill patients, and identify those patients likely to develop ARDS. Thus, the serum acyl ratio may not only prospectively identify and facilitate the assessment of new treatments in patients at highest risk for developing ARDS, but may also lead to new insights about the pathogenesis of ARDS."

Tucker can be found at:

Twitter - https://twitter.com/tuckergoodrich

Blog - http://yelling-stop.blogspot.com/

Ally can be found at:

Twitter - https://twitter.com/paleocanteen

Twitter - https://twitter.com/paleoally

Instagram - https://www.instagram.com/paleocanteen

YouTube - https://www.youtube.com/c/AllyHouston