Eagle's Eye View: Your Weekly CV Update From ACC.org Marijuana Use & Endothelial Function; CV & Bleeding With Aspirin v. Clopidogrel; Mental Health for Survivors of SCA and ICD Shock
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Jun 11, 2025 This week, the discussion dives into how chronic marijuana use impairs endothelial function. The hosts compare the bleeding risks and effectiveness of aspirin versus clopidogrel in treating acute coronary syndromes. Additionally, they highlight the often-overlooked mental health challenges faced by survivors of sudden cardiac arrest, particularly those dealing with the aftermath of ICD shocks. The need for comprehensive mental health support in these cases is emphasized.
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Marijuana Harms Endothelial Function
- Marijuana use impairs endothelial function as shown by reduced flow-mediated dilation.
- Smoking marijuana causes more endothelial dysfunction than edible use, with effects increasing by dose.
Aspirin vs Clopidogrel in ACS PCI
- Aspirin and clopidogrel showed no significant difference in cardiovascular or bleeding outcomes post-PCI for ACS.
- Patients who developed ACS on aspirin might benefit from a different or dual antiplatelet therapy.
Prioritize Mental Health Post-SCA
- Assess mental health symptoms in sudden cardiac arrest survivors and ICD shock patients.
- Provide behavioral follow-up, rehabilitation, family support, and outreach to address PTSD and improve quality of life.