In COVID-19 clinical update #48, Daniel Griffin reviews effect of spike amino acid changes on neutralization with monoclonal antibodies, Sputnik V safety and efficacy results, increased reactogenicity after a single vaccine dose in seropositive individuals, single dose vaccination in seropositive health care workers, and results of three clinical trials on the use of anticoagulants.

Hosts: Daniel Griffin and Vincent Racaniello

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Links for this episode

Resistance of variants to mAb neutralization (bioRxiv)
Safety and efficacy of Sputnik V (Lancet)
Increased vaccine reactogenicity in seropositives (medRxiv)
Single dose vaccination in seropositive health care workers (medRxiv)
Update on vaccine intervals (CDC)
Single dose AZD1222 results (Lancet preprints)
Three RCT on anticoagulants (NIH)
Letters read on TWiV 716
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 716: COVID-19 clinical update #48 with Dr. Daniel Griffin