In this week’s episode of "The Top Line," Fierce Deputy Editor Andrea Park and Fierce Biotech Senior Editor Gabrielle Masson discuss how workforce reductions impacted the biopharma industry in the first quarter.

The pair examine industry trends, company closures, developments in the cell and gene space—and the reductions in force happening at federal health agencies alongside them.

To learn more about the topics in this episode:

Biopharmas laid off staffers at least 63 times in Q1: Fierce Biotech analysis
Fierce Biotech Layoff Tracker 2025: Pfizer sells site, cuts staff; Opthea reduces workforce by 65%

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Q1 biopharma layoff trends, plus expectations for Q2