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(0:00) Introduction to Neil Datta and Optima Asset Management (1:07) Neil Datta's background and role at Optima (2:13) Due diligence and evaluating management companies (4:54) Venture capital skepticism and infrastructure issues (7:25) Diligence differences: public vs. private markets (9:43) Access, flywheel effect, and endowment strategies in VC (14:22) Understanding venture capital as an alternative asset class (16:06) Sponsor: AngelList (17:24) Portfolio diversification and lessons from past crises (20:27) Diversification strategies within venture capital stages (21:39) Bullish sectors and opportunities in biotech venture (24:00) Insights on the human genome project and early stage biotech (25:21) Emerging general partners and fundraising transparency (28:13) LP expectations, scrutiny, and liquidity strategies (32:24) Anticipating SEC guidelines and their impact on the industry (33:30) Managing LP relationships and venture capital fee structures (37:04) Optima's STAR program and final thoughts (39:39) Podcast outro