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Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
Episode 254: Keywords Part 22: Dystrophies and Trisomy 21
May 8, 2023
Dr. Gillian Isaac discusses muscular dystrophies and trisomy 21, covering topics like anesthetic management strategies, risks for malignant hyperthermia, drug sensitivities, bradycardia in trisomy 21 patients, and Disney World trip mishaps.
39:09
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Quick takeaways
- Patients with muscular dystrophy are at risk of perioperative complications due to triggering agents like succinylcholine, requiring careful intraoperative management.
- Understanding conditions associated with malignant hyperthermia susceptibility is crucial for safe anesthetic care in patients with specific disorders.
Deep dives
Patients with Muscular Dystrophy: Anesthetic Risks
Patients with muscular dystrophy, such as Duchenne and Becker muscular dystrophy, are at risk for perioperative complications due to triggering agents like succinylcholine that can induce skeletal muscle breakdown, leading to hyperkalemia and rhabdomyolysis. Intraperative management involves avoiding triggering agents and considering cardiac conduction abnormalities, hypersensitivity to anesthetics, and metabolic abnormalities.
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