Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast Episode 254: Keywords Part 22: Dystrophies and Trisomy 21
May 8, 2023
Dr. Gillian Isaac discusses muscular dystrophies and trisomy 21, covering topics like anesthetic management strategies, risks for malignant hyperthermia, drug sensitivities, bradycardia in trisomy 21 patients, and Disney World trip mishaps.
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Muscular Dystrophy Key Risks
- Duchenne and Becker muscular dystrophies cause painless, symmetric skeletal muscle weakness due to dystrophin mutation.
- These patients are at risk for life-threatening perioperative complications triggered by succinylcholine and volatile anesthetics.
Use Anki for Memorization
- Use Anki flashcards for memorizing difficult anesthesia facts like malignant hyperthermia susceptibility.
- Anki helps by repeating missed cards more frequently, improving retention efficiently.
Myotonia Disorders Differ
- Myotonia congenita and myotonic dystrophy are distinct disorders with different anesthetic implications.
- Myotonic contractions in myotonia congenita can be relieved by sodium channel blockers like procainamide.