

Biochemistry & Molecular Biology of Serotonin Receptors, Tryptamines & Psychedelics | Ryan Gumpper | 102
Jan 12, 2023
01:14:39
Nick talks to biochemist & biophysicist Dr Ryan Gumpper, a postdoc in Dr. Bryan Roth's lab at the University of North Carolina. They discuss the biochemistry, molecular biology & biophysics of serotonin receptors, including the molecular details for what happens when serotonin and tryptamines psychedelics (e.g. LSD) bind to 5HT2A receptors in the brain. They also discuss how understand these details relates to the quest to discover novel psychedelic-derived compounds with therapeutic benefits, as well as the inspiration Ryan received from reading Alexander Shulgin's famous book, PIHKAL.
*Not medical advice.
Affiliates:
- Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.
- AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link.
- KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)
- Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
- SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount.
- MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off
For all the ways you can support my efforts