The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer's Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

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Links for this episode

Virology Comics on sale (Amazon)
Clinical Trial: antiviral for AD
HHV6 and HHV7 transcripts in AD brain (TWiV 505)
HSV1 in AD (Front Ag Neuro)
Taiwan cohort study on antivirals and AD (Neurother)
HSV1 antibodies in CSF (J Med Virol)
HSV1 induces amyloid-beta fibrillization (Neuron)
Image credit
Letters read on TWiV 519
Timestamps by Jolene. Thanks!

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Intro music is by Ronald Jenkees.

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TWiV 519: Fishing for viruses in senile