MCAT Basics (from MedSchoolCoach)

Glycolysis

Jun 24, 2025
Join educator Alex Starks as he breaks down glycolysis, a key metabolic pathway for energy production. He explains glucose digestion, insulin's role in glucose uptake, and the intricate steps of glycolysis. Dive into the conversion of glucose to energy, including NADH and ATP generation. Alex also shares effective study strategies for MCAT test-takers, highlighting common question types and techniques for mastering complex topics. Perfect for anyone looking to enhance their understanding of metabolism!
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INSIGHT

Metabolism As Electron Flow

  • Metabolism is best viewed through electron flow and redox reactions.
  • Catabolism strips electrons from fuels and often funnels them to the ETC to make ATP.
INSIGHT

Liver Gets First Pass Of Glucose

  • Glucose from the gut first travels to the liver via the hepatic portal vein.
  • The liver uses GLUT2, which transports glucose based on concentration (KD), affecting uptake dynamics.
INSIGHT

Insulin-Dependent GLUT4 Uptake

  • Skeletal muscle and adipocytes require insulin to take up glucose via GLUT4.
  • The brain does not depend on insulin for glucose uptake.
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