The Skeptics' Guide to the Universe The Skeptics Guide #1066 - Dec 13 2025
22 snips
Dec 13, 2025 This discussion dives into the rising rates of early-onset cancers and the debate surrounding screening methods. The hosts explore how modern living is impacting human biology through pollution and changes in microbiomes. A significant mRNA vaccine safety study reveals good news about COVID mortality. They also tackle the implications of cosmic rays that recently grounded flights. Additionally, the critique of celebrity 'reverse aging' claims and insights on EU gene editing regulations provide thought-provoking insights into the future of health and technology.
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Target Screening, Don't Over-Screen
- Do weigh screening benefits against harms: more sensitive imaging finds asymptomatic lesions that may never cause problems.
- Use family history and risk algorithms to target screening rather than casting a very wide net.
Modern Environments vs. Evolutionary Biology
- Modern built environments drastically differ from ancestral settings and may undermine biological systems that support fitness.
- Reduced microbial exposure plus air, light, and noise pollution plausibly harm reproduction and immune function.
Optimize Light And Advocate Locally
- Try to increase daytime outdoor light exposure and dim lights at night to support circadian rhythms and sleep.
- Advocate for cleaner air, lower noise, and equitable green spaces to reduce systemic environmental health harms.
