Mikkipedia Mitochondria, Stress, and the Truth About Healing with Curtis Gillespie Sayers
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This week on the podcast, Mikki speaks to Curtis Gillespie Sayers for a wide-ranging and grounded conversation on chronic illness, mitochondrial health, and what real healing actually requires.
Curtis shares his own health journey — from being in and out of hospital from a young age with severe sleep apnoea, cardiometabolic risk, and long-standing physiological stress, to entering the health space through bodybuilding before realising that looking fit and being well are not the same thing.
Together, they explore why many people remain stuck despite doing “all the right things,” and how healing often fails not because of a lack of effort, but because the body is still operating in a defensive state. They discuss the physiology that keeps the body stuck in survival rather than being able to heal. They also dive into peptides, what is and isn’t appropriate and Curtis’ recommendations for out of the box treatments.
Curtis Gillespie Sayers is a health practitioner and systems thinker specialising in mitochondrial health, nervous system regulation, and recovery from chronic illness.
After spending much of his early life in and out of hospital with significant respiratory and cardiometabolic complications — including severe sleep apnoea, hypertension, dyslipidaemia, and pre-diabetic markers — Curtis entered the health space initially through bodybuilding. While improving his physique helped some symptoms, it also revealed a deeper truth: external fitness does not guarantee internal health.
Driven by a desire to understand what was happening beneath the surface, Curtis shifted his focus toward the interaction between mitochondria, the nervous system, immune signalling, and environmental inputs such as light, sleep, and stress. His work now centres on helping people who feel “stuck” — those who have tried diets, supplements, and protocols without lasting improvement — by addressing the biological signals that determine whether the body can actually heal.
Curtis takes a pragmatic, data-informed approach, viewing tools like nutrition, supplements, and peptide therapy as supportive levers rather than shortcuts, and emphasising the importance of safety, adequacy, and rhythm in long-term recovery.
Curtis https://lifestylempowerment.ca/
Curtis https://www.instagram.com/funct.med.curtis/
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