Talking Biotech with Dr. Kevin Folta

The Shingles Vaccines and Dementia - Dr. Pascal Geldsetzer

10 snips
Jul 19, 2025
Dr. Pascal Geldsetzer, an Assistant Professor at Stanford's Knight Initiative for Brain Resilience, shares groundbreaking research on the shingles vaccine's potential to prevent dementia. They delve into the surprising link between shingles vaccination and cognitive decline, emphasizing its importance for older adults. The discussion also highlights alarming dementia prevalence and the challenges of current treatments. With data indicating that vaccination may significantly reduce dementia risk, the conversation underscores the urgent need for further research and community support.
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ANECDOTE

Kevin Folta's Shingles Vaccine Anecdote

  • Kevin Folta experienced the pain of shingles through friends who suffered from it and decided to get vaccinated himself.
  • His personal encounter sparked his curiosity to explore the link between shingles vaccination and dementia prevention.
INSIGHT

Shingles Virus Reactivation Explained

  • The shingles virus remains dormant in the nervous system after chickenpox infection and can reactivate with age or immune weakening.
  • Reactivated virus causes painful rashes and nerve pain, which can be debilitating despite not being typically fatal.
INSIGHT

Dementia Burden in Aging Societies

  • Dementia incidence is expected to rise sharply in aging societies due to strong age association.
  • Dementia causes significant health and economic burdens because it requires long-term intensive care.
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