The Healthtech Podcast #420 Dan Jamieson from Biorelate: How AI is Discovering New Drugs Faster Than Ever
Oct 22, 2025
Dan Jamieson, Founder and CEO of Biorelate, shares insights on leveraging AI for drug discovery. He discusses how his PhD led to a partnership with Pfizer, boosting their target proposal success. Jamieson explains the significance of connecting disparate research to unveil new hypotheses and the evolution of Biorelate’s services into a scalable licensing model. He emphasizes the crucial role of domain expertise in tackling complex biomedical challenges, while highlighting AI's ability to complement, not replace, human scientists in this innovative field.
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Pain Interactome Proved Real Value
- Dan built a 'pain interactome' during his PhD and used it to propose drug targets to Pfizer.
- Pfizer doubled their hit rate on proposed targets, proving the approach's value.
Stitching Papers Produces New Knowledge
- Stitching disparate research yields multi‑hop inferences that create new knowledge.
- Combined causal links can reveal effects no single paper states directly.
Adopt Entrepreneurial Habits Fast
- Surround yourself with entrepreneurs to learn startup norms and behaviours quickly.
- Seek mentors and co‑founders to share workload and avoid solo‑founder pitfalls.