Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast
Hormones and mast cells with Dr. Tania Dempsey
Oct 27, 2024
Discover how hormonal changes impact mast cells during key life stages like puberty, pregnancy, and menopause. Dr. Dempsey discusses the intricate relationship between hormones and mast cell activation syndrome. Gain insights into personalized treatment strategies that include hormonal therapies and lifestyle adjustments. Learn how understanding this connection can alleviate symptoms and improve overall well-being.
34:17
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Quick takeaways
- Hormonal fluctuations during puberty, pregnancy, and menopause significantly influence mast cell activation and symptoms in women with MCAS.
- The interplay between conditions like PCOS and MCAS highlights the importance of managing insulin resistance for overall mast cell stabilization.
Deep dives
Hormonal Influences on Mast Cell Activity
Mast cells play a crucial role in the immune system, responding to various environmental changes, including hormones. They possess receptors for a range of hormones such as estrogen, progesterone, and testosterone, which can influence their activation. For instance, estrogen may stimulate mast cell activity, while progesterone has been suggested to stabilize them. These hormonal interactions are particularly significant during key life stages for women, such as puberty, menstruation, pregnancy, and menopause, often leading to increased symptoms for those with mast cell activation syndrome (MCAS).
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