Morning Wire The Hormone Reset: FDA’s New Approach to Women’s Medicine
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Nov 22, 2025 Discover a groundbreaking shift in hormone replacement therapy as the FDA updates its guidance for menopausal women. Hear from the FDA Commissioner about the removal of black box warnings and the potential long-term health benefits of timely hormone therapy. Learn about new FDA-approved medications and what's in store for menopausal symptom relief. The discussion also touches on broader public health initiatives, including dietary recommendations and faster therapies. Get the latest insights on women's health!
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Reframing Hormone Replacement Benefits
- The FDA is removing black box warnings that scared women from estrogen products and reframing HRT benefits.
- Estrogen started within 10 years of menopause may cut fractures, fatal heart attacks, and cognitive decline substantially.
Start HRT Early For Best Outcomes
- Start hormone replacement therapy within about 10 years of menopause for the best risk-benefit ratio.
- Many doctors continue therapy for life when begun near menopause to preserve cardiovascular and cognitive benefits.
Contraindications And Safer Delivery Options
- Active breast cancer remains a clear contraindication, while other risks are now considered relative.
- Alternatives like topical gels or vaginal forms can reduce clot risk for predisposed women.