
Reading Our Times How does life work? In conversation with Philip Ball
Oct 28, 2025
In this enlightening discussion, science writer Philip Ball, author of *How Life Works*, challenges the traditional gene-centric view of life. He argues that the DNA blueprint metaphor is misleading and emphasizes that life functions on multiple levels. Ball explores how cells act as decision-makers with agency, using contextual information to thrive. He also delves into the implications for disease treatment, urging a shift from genetic solutions to more holistic approaches. Lastly, he reflects on the profound mystery of consciousness and the true meaning of purpose in living beings.
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Genome Is Not A Blueprint
- The genome-as-blueprint metaphor misleads because DNA alone doesn't determine organismal form and function.
- Molecular biology shows life is not purely bottom-up but involves multi-level interactions and context.
History Killed Vitalism
- Philip Ball recounts the historical decline of vitalism as chemistry and Pasteur's work showed living matter obeys physical laws.
- This history supports treating life as material yet distinct in emergent behaviour.
Causality Spreads Across Levels
- Cells use genomic resources but make decisions about which resources to use based on context.
- Causality in biology spreads across levels rather than residing only in genes.









