The Curbsiders Internal Medicine Podcast

#424 Hotcakes: Transfusion in Acute MI, COVID-19 Rebound after Paxlovid, Every-other-day Iron Revisited, Oral Phenylephrine Doesn’t Work, and Stop Correcting Serum Calcium

Jan 29, 2024

In this podcast, the hosts cover a range of intriguing topics including transfusion thresholds in acute MI, COVID-19 rebound after treatment with nirmatrelvir, the prevalence of iron deficiency, the ineffectiveness of oral phenylephrine, and the liberal vs restrictive transfusion strategy in MI. They also discuss challenges in transfusion decision making, highlight the unreliability of corrected calcium levels, and explore iron supplementation for anemia. A humorous introduction and calcium puns add entertainment to the episode.

Ask episode

Chapters

Transcript

Episode notes

Introduction

00:00 • 2min

Iron Deficiency and Anemia in Young Women

01:33 • 13min

Corrected Calcium Levels and Their Reliability

14:27 • 7min

Virologic Rebound after Antiviral Treatment for Acute COVID

21:19 • 19min

The MINT Trial: Liberal vs Restrictive Transfusion Strategy

40:29 • 6min

Challenges in Transfusion Decision Making

46:35 • 8min

Wrap-up and Acknowledgments

54:29 • 2min

Join us as we review recent practice-changing articles on transfusion thresholds in acute MI, COVID-19 rebound after treatment with ritonavir-boosted nirmatrelvir (PaxlovidTM), the prevalence of iron deficiency, as well as the debut of our new “corrections and omissions” section, in which we cover important knowledge updates on oral iron dosing and correcting serum calcium. And, find out why oral phenylephrine does not work and what you should prescribe instead for upper respiratory symptoms. Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), and Matt Watto (@doctorwatto).

Claim CME for this episode at curbsiders.vcuhealth.org!

Episodes | Subscribe | Spotify | Swag! |Mailing List | Contact | CME!

Credits

Written, Produced, and Hosted by: Rahul Ganatra MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP
Cover Art: Matthew Watto MD, FACP
Reviewer: Rahul Ganatra MD, MPH
Technical Production: Pod Paste
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Show Segments

00:00 Introduction and Calcium Puns
03:11 Iron Deficiency and Iron Supplementation
12:20 Corrected Calcium
18:09 Virologic Rebound after nirmatrelvir/ritonavir (Paxlovid™)
32:09 Phenylephrine and its Ineffectiveness
37:00 Restrictive vs. Liberal Transfusion Strategy in MI (MINT trial)
49:20 Outro

Transcript Disclaimer
We've included a a free AI-generated transcript which has not been corrected by a human for accuracy or completeness. Please consider this a starting point for further research and consultation. We disclaim any liability for damages or losses resulting from this content.

Sponsor: Rocket Money

Cancel unwanted subscriptions by going to RocketMoney.com/CURB

Sponsor: Netsuite

Download NetSuite’s popular KPI Checklist, designed to give you consistently excellent performance for free, at NetSuite.com/CURBSIDERS

Sponsor: Freed

You can try Freed for free right now by going to freed.ai. And listeners of Curbsiders can use code CURB50 for $50 off their first month.