Living to 100 Club

The Sinclair Method: An Innovative Approach to Reduce Excess Drinking with an FDA-approved Medication

Apr 6, 2023
Brian Noonan, a nurse practitioner specializing in addiction treatment, shares insights on the Sinclair Method, a groundbreaking approach to reducing alcohol consumption using FDA-approved naltrexone. He explains how this method diminishes the pleasurable effects of drinking without requiring abstinence. Brian discusses the complexities of treating alcohol use disorders and the positive impact of off-label medication use. His passion shines through as he emphasizes the importance of fostering a healthier relationship with alcohol and the convenience of accessing this treatment through telehealth.
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ANECDOTE

Brian's Path to Addiction Treatment

  • Brian Noonan's journey began with a student job at an addiction treatment center.
  • This led him to specialize in addiction treatment, including the Sinclair Method.
INSIGHT

Traditional Naltrexone Treatment

  • Traditional naltrexone treatment for alcohol use disorder focuses on abstinence.
  • A 2001 study in the New England Journal of Medicine showed it to be ineffective for chronic alcohol dependence.
INSIGHT

How Naltrexone Works

  • Naltrexone blocks opioid receptors, preventing the pleasurable effects of opioids and alcohol.
  • Alcohol releases endorphins, our natural opioids, which is why we enjoy its effects.
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