Prolonged Field Care Podcast

SOMSA '25 (Research) - Transfusion Reaction Data

Oct 1, 2025
A deep dive into transfusion reactions in trauma patients reveals critical insights. Only 0.3% of cases showed reactions, yet those needing massive transfusions faced a higher likelihood. Most reactions occurred on the first day, with explosive injuries linked to increased rates. The discussion highlights the gap in data, emphasizing the need for more comprehensive registries and collaboration with civilian counterparts. While transfusions dramatically improve survival, understanding the risks and refining procedures is essential for enhancing patient outcomes.
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ANECDOTE

Team Effort To Pull Sparse Data

  • Adam Spanger did most of the data work and slides for the analysis.
  • Ashley and Kermashow helped gather and analyze scarce transfusion reaction data.
INSIGHT

Massive Transfusion Raises Reaction Risk

  • Patients needing massive transfusions are more likely to develop transfusion reactions.
  • The survival benefit from transfusion far outweighs the risk of reactions.
INSIGHT

Civilian Rates Don't Translate Directly

  • Civilian data show transfusion reaction rates around 1% and lower mortality with reactions.
  • Military trauma data are limited and often mix medical and trauma transfusions.
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