Empowered Patient Podcast Bringing Nanophysics to Cancer Radiation Therapy with Laurent Levy Nanobiotix
Laurent Levy is the CEO of Nanobiotix, which is applying nanophysics to direct radiation therapy more efficiently to cancerous tumors while reducing the side effects of damage to surrounding tissue. This intratumoral injection of nanoparticles maximizes the concentration in the tumor and minimizes the rest of the body exposure. Starting with soft tissue sarcoma, they are expanding to head and neck cancer with plans for other indications like pancreatic, liver, and breast cancer.
Laurent explains, "We thought, at Nanobiotix, that we may find something different. Rather than making better radiation therapy equipment, we thought about the problem in a different way. We did develop a product that is an injectable that you will inject directly into the tumor. And, when the product is in the tumor -- they are based on nanoparticles, tiny objects -- these objects will go into the cell, and they will sit there. They'll do nothing until the patient is getting the usual radiation therapy."
"And we've been designing those objects to be able to absorb the energy of radiation. Therefore, when the patient is getting radiation, the x-ray will cross the cancer cell, and the nanoparticle in that cancer cell will absorb the energy and will deliver around them a high quantity of damage and will kill the cancer cell more efficiently."
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