Programming life: An interview with Jennifer Doudna

The Bio Revolution has the potential to transform our lives, and genome editing—the ability to change the DNA sequence in a targeted way using CRISPR-Cas9, is one of the key innovations that has sparked imaginations while also raising its fair share of controversy. What is the origin of this technique? How do we weigh the enormous benefits against the potential risks? And what is its role in solving the global coronavirus pandemic? As part of the McKinsey Global Institute’s research on the Bio Revolution, partner Michael Chui spoke with Jennifer Doudna, PhD, one of the scientists who discovered the genome-editing technique CRISPR-Cas9 and leading proponent of its responsible use. Jennifer is a professor of molecular and cell biology and chemistry at the University of California, Berkeley. The Doudna lab pursues a mechanistic understanding of fundamental biological processes involving RNA molecules.

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