

REPLAY: Turning Back Time with Bryan Johnson (Brave New World preview)
Feb 27, 2025
In this engaging discussion, Bryan Johnson, an entrepreneur dedicated to extending human lifespan through his initiative, Project Blueprint, shares his ambitious journey. He reveals his radical approach to reverse biological aging, likening it to a modern adventure. Johnson delves into cutting-edge therapies and biomarkers that indicate progress in health and aging. Alongside Dr. Oliver Zolman, they tackle the philosophical impacts of AI on our purpose and existence, raising intriguing questions about humanity's future in the face of rapid technological advancements.
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Early Inspiration
- Bryan Johnson's transformative experience living in poverty in Ecuador at 21 fueled his desire to make a meaningful impact.
- This led him on an entrepreneurial path, culminating in the sale of Braintree Venmo for $800 million.
Learning from History
- Bryan Johnson's main learning source is biographies, finding traditional schooling slow and unengaging.
- He believes methodical processes can lead to impactful discoveries.
Experimental Approach
- Dr. Oliver Zolman, Johnson's doctor, uses Johnson as a "guinea pig" to test various experimental therapies.
- They meticulously document and monitor both safety and efficacy using biomarkers and advanced imaging.