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The Big Story
Could a Canadian breakthrough lead to an ALS cure?
Jun 7, 2024
Discover the groundbreaking ALS research by Western University, offering hope for a cure. Learn about the new protein RGNF that shows promise in halting motor neuron death. Explore the emotional toll of ALS on patients and caregivers, and the challenges in developing effective treatments. Dr. Michael Strong shares insights on the impact of ALS and the advancements in managing symptoms.
26:24
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Quick takeaways
- Researchers have identified a protein imbalance in ALS that can restore cellular balance and functionality.
- Potential clinical trials in humans for ALS treatment could start within the next three to five years.
Deep dives
Understanding ALS - A Devastating Neurological Disease
ALS, also known as Lou Gehrig's disease, affects around 4,000 Canadians and is part of the big three diseases of aging alongside Alzheimer's and Parkinson's. It primarily impacts nerve supply to muscles, causing weakness and wasting, leading to respiratory failure within three to five years. Living with ALS is described as progressively debilitating, affecting motor function, speech, and swallowing, profoundly impacting both patients and their caregivers.
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Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode