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emDOCs.net Emergency Medicine (EM) Podcast

Episode 93: BRASH Syndrome

Jan 23, 2024
Delving into BRASH Syndrome, the podcast covers the complexities of diagnosis and treatment including manifestations, triggers, and comprehensive management in the ED. It explores the critical relationship between hyperkalemia, bradycardia, and renal injury, emphasizing the importance of early recognition and proper interventions.
17:02

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Quick takeaways

  • BRASH syndrome involves synergy between hyperkalemia and AV nodal blockers causing bradycardia, renal failure, shock.
  • Common medications like ACE inhibitors, ARBs, beta blockers contribute to Brash syndrome by increasing hyperkalemia risk.

Deep dives

Understanding Brash Syndrome

Brash syndrome is characterized by the synergistic relationship between hyperkalemia and AV nodal blockers, leading to bradycardia, renal failure, shock, and hyperkalemia. This condition can occur even with mild hyperkalemia and normal doses of AV nodal blockers, impacting cardiac output and renal blood flow.

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