Neurology Exam Prep Podcast Episode 3 - Neuromuscular Disorders Part I
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Jan 14, 2020 In this engaging discussion with Jeff Dewey, an assistant professor of neurology, listeners dive deep into the realm of neuromuscular disorders. Topics include the differentiation of motor neuron diseases through EMG findings and the clinical features of ALS and spinal muscular atrophy. Dewey also addresses the symptomatic management of ALS, touching on nutritional support and ventilation strategies. With insights into brachial plexus disorders and the complexities of neuropathy diagnosis, this conversation equips medical trainees with vital knowledge for their careers.
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ALS Diagnosis Criteria
- ALS combines upper motor neuron signs like spasticity with lower motor neuron signs such as atrophy and fasciculations.
- Diagnosis relies on detecting these symptoms across multiple nervous system segments like bulbar, cervical, and lumbar.
EMG Clues for Motor Neuron Disease
- EMG usually shows normal sensory studies but decreased motor amplitudes in ALS.
- Early denervation in paraspinal muscles is a key EMG clue for motor neuron disease.
Variants of ALS
- ALS variants like primary lateral sclerosis and progressive muscular atrophy differ by predominance of upper or lower motor neuron signs.
- They are painless and lack sensory symptoms, helping differentiate from other diagnoses.