Innovation Meets Compassion – Fernando Vieira

In this inspiring episode of SpreadLove in Organizations, in partnership with the Termeer Institute, host Naji Gehchan welcomes Dr. Fernando Vieira, CEO and Chief Scientific Officer of the ALS Therapy Development Institute (ALS TDI). A physician-scientist and engineer, Fernando shares his deeply personal journey from aspiring inventor to leading one of the world’s foremost non-profit biotechs dedicated to ALS. His passion stems from the loss of his close friend to the disease, which shaped his life’s mission - to translate scientific discovery into real treatments for people living with ALS.

Fernando offers an inside look into the unique non-profit biotech model at ALS TDI -an organization that combines scientific rigor with mission-driven purpose. With integrated research programs spanning cell biology, pharmacology, and clinical data, ALS TDI develops and validates therapeutic targets, often spinning off intellectual property to for-profit partners to advance drug development. Fernando highlights the advantages of staying focused on a single disease area, building institutional knowledge, maintaining long-term commitment, and ensuring every effort serves the ALS community. He also explores the promise and challenge of rare disease research, emphasizing the complexity and need for multiple targeted therapies to address ALS’s many subtypes.

Looking ahead, Fernando expresses optimism about emerging technologies, AI applications, and omics data transforming ALS research. From digital biomarkers and machine learning to novel therapeutic modalities, he believes the field is entering a new era of precision and hope. Reflecting on leadership, he defines it as servant leadership: serving the mission and his team with empathy and humility. As a recent Termeer Fellow, he praises the Foundation for fostering mentorship and connection among healthcare innovators.

"Think about the people that you're trying to serve, and meet them where they are. Understand their needs, and let that guide everything you do."

MEET OUR GUESTS Fernando Vieira, CEO and CSO at ALS Therapy Development Institute, Termeer Institute Fellow.

Fernando Vieira has over 20 years of dedication to advancing ALS research and treatment development at the ALS Therapy Development Institute (ALS TDI), a non-profit biotech company. Dr. Vieira has progressed through various leadership roles at ALS TDI, culminating in his current positions as Chief Executive Officer and Chief Scientific Officer. He leads a team of over 25 researchers, overseeing target discovery, drug discovery, biomarker development, and translational ALS research.

Having lost his closest friend to ALS, Fernando is deeply committed to translating scientific discoveries into clinical applications that benefit people with ALS. Fernando’s work integrates preclinical pharmacology, multi-omics, and digital outcome measures, driving the preclinical validation of multiple drugs, including tegoprubart, now in clinical development for ALS, along with kidney transplant. He has worked to establish ALS TDI as a hub for innovative ALS research infrastructure, fostering collaborations to enhance disease monitoring and therapeutic outcomes.

Fernando is a recognized leader in ALS research, affirmed by his roles on the Research Committee of ALS ONE and the International Alliance of ALS/MND Associations Research Directors Forum. He holds multiple patents for novel therapeutic approaches for ALS and has contributed to publications in multiple high impact journals such as Nature Communications, Nature Genetics, and Science Translational Medicine. Fernando earned a degree in biological engineering from the University of Florida and his MD from Harvard Medical School. Outside of his professional life, Dr. Vieira is a dedicated father to a high school-aged son in Newton. He actively participates in his son's activities with a local Scouting America troop. In his free time, he enjoys running, hiking, and playing basketball.