Trauma ICU Rounds

Episode 7 - Shock Talk I: Pathophysiology & Classification

Apr 24, 2020
Dive into the intricate world of shock in trauma care. Discover its dynamic nature and the urgency in identifying patients at risk. Learn about the physiological effects of shock on oxygen delivery and cellular health. Explore a straightforward classification system, breaking down hypovolemic, cardiogenic, distributive, and obstructive shock. Understand the vital differences between compensated and uncompensated shock, setting the stage for effective treatment strategies. This insightful discussion is essential for any trauma practitioner.
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INSIGHT

Understanding Shock

  • Shock is inadequate oxygen/nutrient delivery for normal tissue/cellular function, creating a supply/demand imbalance.
  • This imbalance, if unrecognized or underappreciated, can lead to serious complications for patients.
INSIGHT

Cellular Respiration and Shock

  • Healthy cellular respiration produces ATP using oxygen, yielding 32 ATP per glucose molecule.
  • Shock impairs this, forcing anaerobic glycolysis with less ATP and lactate buildup.
INSIGHT

Oxygen Extraction and Critical DO2

  • When oxygen delivery (DO2) decreases, oxygen extraction ratio increases to maintain cellular metabolism.
  • Beyond a critical DO2, oxygen consumption decreases, leading to dysoxia and tissue hypoxia.
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