TWiV discusses the finding that the envelope (E) protein of SARS-CoV-2 is sensed by toll-like receptor 2 on cells, leading to the production of inflammatory cytokines that cause damage to cells and tissues in COVID-19.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Links for this episode

ASV vaccine town halls
Michelson Prizes
FDA authorizes Pfizer/BioNTech mRNA vaccine for adolescents (FDA)
TLR2 senses SARS-CoV-2 E protein (Nat Imm)
Review on CoV E protein (Virology J)
Timestamps by Jolene. Thanks!

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Brianne – Lab.Hacks Lab Assistant App Rich – Weird viral DNA spills secrets to biologists; COVAX Kathy – Planet Earth Now Vincent – Variants at ViralZone

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

TWiV 754: Tuesday two: SARS-CoV-2 and TLR2