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Critical Care Reviews Podcast
COCA Trial Results Presentation
Dec 6, 2021
Drs Mikael Fink Vallentin and Lars Andersen present the results of the COCA trial investigating calcium for out-of-hospital cardiac arrest. They discuss the use of calcium as a potential intervention, trial methodology and results, patient outcomes, and the need for further research.
29:34
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Quick takeaways
- The COCA trial results showed that calcium administration during out-of-hospital cardiac arrest did not significantly improve the return of spontaneous circulation (ROSC) or survival rates at 30 days compared to the placebo group.
- The trial results indicated that calcium did not have a significant impact on the quality of life for out-of-hospital cardiac arrest survivors at both 30 days and 90 days after the event.
Deep dives
Primary Outcome: Return of Spontaneous Circulation
The trial investigated the use of calcium during out-of-hospital cardiac arrest, aiming to improve the return of spontaneous circulation (ROSC). However, the results showed that there was no statistically significant difference in ROSC between the calcium group and the placebo group. The percentage of patients with ROSC was 19% in the calcium group and 27% in the placebo group.
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