Gastroenterologist Mark Pimentel discusses his article, "SIBO and IBS: the hidden link keeping millions in pain." Mark explains how small intestinal bacterial overgrowth (SIBO) is frequently misdiagnosed or overlooked due to its symptom overlap with other GI conditions, particularly irritable bowel syndrome (IBS). He outlines the evolution of diagnostic tools like hydrogen, methane, and hydrogen sulfide breath tests, the clinical relevance of new ICD-10 codes, and the FDA-approved treatment rifaximin. Mark emphasizes that the most effective treatment remains the elemental diet—now made more palatable thanks to food science innovation. He urges increased awareness, clinician education, and research to bring this hidden condition to light and improve patient outcomes.

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Why SIBO is often misdiagnosed as IBS