Dr. Joseph Mercola - Take Control of Your Health

Butyrate: Your Gut's Secret Weapon for a Healthy Brain

Mar 24, 2025
Discover the power of butyrate, a gut-derived compound that helps boost brain health and combat neuroinflammation. This nutrient is key in regulating neurotransmitters like GABA and serotonin, impacting mood and cognitive function. Learn how the gut-brain axis relays butyrate signals, influencing stress and immunity. Emphasizing dietary fiber and homemade ferments, the discussion reveals how to optimize gut health for better mental well-being. Unveil the vital connection between gut microbiome and brain wellness for a happier, healthier life.
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INSIGHT

Butyrate's Role

  • Butyrate, a gut-produced molecule, acts as a messenger in the gut-brain axis.
  • This axis involves neurotransmitters, hormonal signals, immune signals, and metabolic signals.
INSIGHT

Butyrate and Neuroinflammation

  • Butyrate reduces neuroinflammation, which is linked to cognitive decline and neurodegenerative diseases.
  • It inhibits inflammatory pathways like NF-kappaB, and enzymes called HDACs.
INSIGHT

Butyrate's Impact on Diseases

  • Studies indicate butyrate may help clear amyloid beta plaques in Alzheimer's.
  • It also impacts dopamine-producing neurons in Parkinson's, improving energy metabolism.
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