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Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD—a randomized controlled trial

Show Notes:

Fact-Checking Gary Brecka on Rogan: A Deep Dive into MTHFR and Methylation

Grayson Strange on Instagram

Questions:

Lifting Philosophy Changes

Kevin writes:

Hi Robb and Nicki.

First time question submitter, but I am a huge fan as I have been following your work since 2012. I am an active 35 year old male, 5'10", and about 165-170lbs. I eat whole foods, walk about 9,000-12,000 steps/day, lift 5x/week (switched to bodybuilding split for joint recovery), and most importantly train Jiu Jitsu 4x/week. I am very conscious with respect to my training and lifting as I would like to make this a lifetime practice. I have been training Jiu Jitsu for a little over 8 years and lifting about 12 years. I am always thinking about longevity and how I can preserve my body to the best of my ability. Obviously Jiu Jitsu can have other plans and can disrupt this preservation process, which is why I made an effort to switch to a more controlled/"old man" game about 5 or so years ago.

However, my question is more focused on the lifting aspect. I am curious how your philosophy has changed on weight training and what you think would be the best long term solution. I have a home gym with barbells, kettlebells, dumbbells, weight vests, etc., but the older I get the more I realize that recovery and longevity is paramount. I would still like to maintain and/or gain muscle, but I would not like to sacrifice my longevity. How do you tackle this problem nowadays? Are calisthenics with or without a weight vest a good solution? I am always curious to hear your thoughts. I hope Montana has been treating you well and thanks in advance!

Fungal Rash

Sam writes:

Hello! Love you guys and all the info and perspective you put out. Hoping you can help add some thoughts here. Long story short I have UC that I just can't control well with diet and lifestyle- 2 years ago, yes TWO YEARS I was put on humira when I first noticed an itchy rash on my back. No one could really figure it out back then. While on humira I got septic arthritis in my knee. 4 surgeries a PE and DVT later I was on IV and oral antibiotics for nearly 6 months. As you can imagine that rash got 1000x times worse along with the IBD. Anyway eventually the rash was identified as a pityrosporum folliculitis. Put on oral Fluconazole and ketaconazole creams which worked for a month or so then rash comes back with force. Had a bad UC flare up and put on steroids recently which completely masked the rash, and once off steroids it comes back 100x worse. It's incredibly itchy and irritating. Outside of the antifungals I've tried probiotics like s.boulliard but doesn't help. Besides the IBD I have PCOS I work hard to remain otherwise healthy. Very physically active and eat a healthy diet mostly paleo but because Im gallbladder less and don't tolerate much fat, and do all the things to prioritize sleep, getting outside and supporting well being. Any thoughts on this rash that won't quit. I clearly have an underlying process going on that the FOUR goddamn dermatologists I have seen for this are completely clueless on. Thanks for any input!

High Blood Pressure

Sissy writes:

Hello Robb,

Long time listener first time caller. Big fan of all that you and Nikki do. Both books have helped me properly wire myself to eat and sacred cow has been a gift I've given to all of my coworkers and friends. So thank you for shedding the light on all things about health for our bodies and the planet.

I've been on a journey of losing a whole human. 523lbs to 265lbs. I'm 6'7 and My blood work done regularly and everything is at peak condition or so my doctor says. Healthy as a Clydesdale they say. A1c is 5.1 and my hdl/tris are in the optimal range and a body fat around 22%. Still high and working on losing the last 30ish pounds. Healthy life style weights 4 times a week zone 2 4 times a week. Eat a 90% paleo diet. Make all my meals at home with The occasional splurge on date night with my wife. Not a drinker and don't smoke. But for some damn reason my blood pressure is still fuckin high 150/105. I've been on beta blocker with no results other than the effects (side effects) of cough itchy through and swelling.

But let me get to the point.

The new Rogan podcast he has Gary breka on and first thing they speak about is high blood pressure so my ears were perked to say the least. Saying most just need to supplement with TMG in order to break down homosistein for well this would get long if I typed it all out. He goes on a tangent of methylation of certain compounds help the body process things we eat to turn them into Things we need. And goes on about 5 gene mutations that certain folks have that doesn't allow for certain proteins/micronutrients to be processed properly.

I'm typically skeptical of all snake oil salesman and even more of the pharmaceutical industry. Whole other convo of docs throwing everyone on a pill that diet and exercise can fix.

Anyway your the scientist and really the only expert I trust with empirical data. So give it to me straight. Am I fucked genetically with hypertension(doc says so) or can it really be as simple as a supplement and vitamin.

Again thanks for all the amazing insights you give for free to the world. I wish you and your family a long, healthy and prosperous life.

Sissy

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Guerillas, Cartels, and Dirty Wars in Mexico, Part 1