

Challenging Cases with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Welcome to this episode of The Oncology Brothers! Drs. Rahul and Rohit Gosain dived into the complexities of relapsed refractory diffuse large B-cell lymphoma (DLBCL) with their new series focused on challenging real-life cases.
In this episode, we are joined by esteemed guests Dr. Carla Casulo from Wilmot Cancer Center and Dr. Tara Graff from Mission Cancer and Blood Center. Together, we explored the current standard of care, including R-CHOP and the role of bi-specific antibodies like epcoritamab and glofitimab.
Key topics covered included:
• When to use bi-specific antibodies and how to manage side effects
• The importance of MRD monitoring in treatment decisions
• Insights on patient management in community oncology settings
• The evolving landscape of treatment options for DLBCL, including CAR-T therapy and clinical trials
We also discuss practical considerations for community oncologists, including the management of cytokine release syndrome (CRS) and the role of immunoglobulin therapy in patients with low IgG levels.
Whether you're a healthcare professional or someone interested in the latest advancements in oncology, this episode is packed with valuable insights and expert opinions.
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