
Multiple Myeloma Hub
Integrating BCMA-directed agents in the treatment landscape for relapsed/refractory MM
Aug 5, 2022
Experts discuss integrating BCMA-directed agents in MM treatment, challenges of CAR T-cell availability, potential of bispecific therapies, and ADCs. Emphasis on managing keratopathy, high response rates with combination therapies, and the importance of evaluating BCMA-directed agents in earlier lines of therapy.
09:13
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Quick takeaways
- Integration of BCMA-directed agents poses challenges for utilizing CAR T-cell products due to availability issues.
- Combination therapies with antibody-drug conjugates (ADCs) and bi-specifics show promise in managing keratopathy and improving patient responses.
Deep dives
Integration of BCMA-Directed Agents in Multiple Myeloma Treatment
Discussing the integration of BCMA-directed agents in the treatment landscape for lapsed refractory multiple myeloma, the podcast explores potential modalities available for managing patients. Speakers consider the challenges of utilizing CART cells due to their availability and propose strategies for maximizing response duration. The conversation highlights the role of off-the-shelf bi-specifics as potential game-changers in treatment and emphasizes the importance of monitoring chronic toxicities in real-world practice.
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