

Ep. 19 - Methoxyflurane, the Green Whistle, with Dr. Ross Hofmeyr
Feb 12, 2025
In this discussion, Dr. Ross Hofmeyr, an anesthesiologist and wilderness medicine expert from South Africa, sheds light on methoxyflurane, a game-changer for pain management in remote settings. He shares the history and practical applications of this anesthetic gas, which boasts efficacy and ease of use, particularly as a 'green whistle' device. Dr. Hofmeyr emphasizes its importance in acute traumatic pain scenarios and discusses the challenges of using it in extreme conditions, making a compelling case for its role in wilderness medicine.
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Methoxyflurane's Unique History
- Methoxyflurane is an old, volatile anesthetic with unique analgesic properties unlike most inhaled anesthetics.
- It was discontinued as an anesthetic due to kidney toxicity at high doses but retained as a potent analgesic.
Safe Self-Administration Basics
- Methoxyflurane inhaler delivers a self-titrated analgesic dose that is safe for adults.
- Patients should self-administer and avoid use via face mask to prevent excessive dosing and respiratory depression.
Methoxyflurane in Wilderness Practice
- Use methoxyflurane primarily for acute traumatic pain in conscious and cooperative patients.
- Train wilderness first responders and guides to administer it safely as a bridge analgesic in remote environments.