Curbside Consults

Management of Acute Coronary Syndrome in Older Adults with Dr. Abdulla Damluji

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Apr 6, 2023
Dr. Abdulla Damluji, interventional cardiologist and associate professor, discusses the management of acute coronary syndrome in older adults. Topics include the challenges of including older adults in clinical trials, manifestations of ACS in older adults, ideal antiplatelet therapy, management of atrial fibrillation, and the importance of a multidisciplinary team in cardiac rehab.
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INSIGHT

Acute Coronary Syndrome Definition

  • Acute coronary syndrome (ACS) involves reduced coronary blood flow due to plaque rupture, causing myocardial injury.
  • ACS ranges from complete blockage (STEMI) to partial blockage (NSTEMI) or unstable angina.
INSIGHT

Older Adults in ACS Studies

  • Older adults, often excluded from clinical trials (75+), experience ACS differently.
  • This statement synthesizes evidence to guide practitioners and researchers.
INSIGHT

Age-Related ACS Risks

  • Age-related cardiovascular changes like aortic stiffness and decreased beta-adrenergic response increase ACS risk.
  • Chronic inflammation and renal issues further complicate matters in older adults.
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