Here's a nice little standalone episode on the life and work of Thomas Wade and Herbert Giles. And you can't mention Herbert Giles without mentioning his son, Lionel Giles. And of course, Robert Morrison must be mentioned as well as all the earliest Western scholars of Sinology going back to Michele Ruggieri. And it wouldn't be fair to only talk about Wade and the two Giles's without giving a nod to their contemporaries elsewhere on the continent and in Asia. So this is a slightly meandering survey of some of the great old sinologists from the 19th century (and early 20th).
