The 2024 Myeloma Landscape with Robert Orlowski, MD, PhD, MD Anderson
Jan 9, 2024
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Dr. Robert Orlowski from MD Anderson discusses the 2024 myeloma landscape, including advancements in CAR-T therapies, bispecific antibodies, and targeted therapies. Topics include risk determination, smoldering myeloma strategies, optimal treatments for newly diagnosed patients, considerations at first relapse, and upcoming clinical trials.
Clinical trials drive advancement in myeloma treatment options.
Deep dives
Personal Reflection on Help Tree Pillars
Help Tree, a program supporting multiple myeloma patients, has three pillars of support: personalized education, patient connections, and a data platform for myeloma researchers. The cutting-edge Help Tree Cure Hub provides anonymized data from over 13,000 patients to aid in treatment optimization.
Advancements in Predictive Gene Research
Research highlights the potential of predictive genes like MIG copy number and LAMP5 expression in identifying high-risk myeloma patients. These findings pave the way for tailored therapies based on genetic profiles, enhancing treatment precision.
Importance of Clinical Trials in Myeloma Care
Clinical trials play a pivotal role in advancing myeloma treatment options, including CAR T-cell therapies and novel drug compounds. These trials offer hope for improved outcomes and personalized therapies for patients at various stages of myeloma.
Impact of Plant-Based Diets on Myeloma
Studies suggest that a plant-based diet may have positive effects on myeloma risk reduction. While not a definitive treatment, adopting such dietary habits could potentially complement standard therapies and contribute to overall health.
Enhancing T-Cell Health and Treatment Sequencing
Improving T-cell health through lifestyle choices and avoiding certain medications may support response to immunotherapies like CAR T-cells. Treatment sequencing decisions based on disease biology, risk factors, and therapy responses play a crucial role in optimizing myeloma care.
The year 2024 brings new promise in multiple myeloma with a wide variety of treatment options avaiable for both newly diagnosed and relapsed/refractory patients. Learn about the progress being made and the very latest in determining risk at diagnosis, strategies for smoldering myeloma patients, optimal treatments for newly diagnosed patients, things to consider at first relapse and beyond. Dr. Robert Orlowski will review advances in CAR T therapies, bispecific antibodies, targeted therapies and combination approaches and clinical trials to watch as the research continues advancing at a rapid pace in myeloma.
Thanks to our episode sponsor, GSK.
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