Rheumnow Podcast

Telling You Where to Go (12.19.2025)

Dec 19, 2025
Discover intriguing connections between Psoriatic Arthritis and Familial Mediterranean Fever. Learn about a groundbreaking GLP-1 trial for knee osteoarthritis that reveals promising results. Uncover how certain lab tests could accurately predict systemic sclerosis-related lung issues. Delve into the importance of skin cancer screenings for immunosuppressed patients. Plus, explore the impact of hydroxychloroquine on ocular toxicity and the yearning for more training among healthcare providers in rheumatology.
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ADVICE

Where To Practice Rheumatology

  • Consider practicing in states with high rheumatology demand like North Dakota, Wisconsin, and Alaska to maximize salary and lifestyle.
  • Jack Cush notes these states rank highly for salary potential, growth, and public health infrastructure.
INSIGHT

GLP‑1 Drugs Might Improve Knee OA Pain

  • A dual GIP/GLP-1/glucagon agonist produced substantial weight loss and large WOMAC pain reductions in obese patients with knee OA at 68 weeks.
  • Jack Cush highlights this phase 3 press-release result as evidence GLP-1–type drugs may help osteoarthritis symptoms.
INSIGHT

IgA Autoantibodies In Rheumatoid Arthritis

  • IgA-RF appears in ~50% of RA patients and IgA-ACPA in 20–40%, with specificity similar to standard tests.
  • Jack Cush says IgA autoantibodies may link mucosal immunity to RA and predict worse outcomes and TNF inhibitor nonresponse.
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