Alta Charo Considers Ethics for Stem Cells and CRISPR
Feb 13, 2024
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Explore the impact of Alta Charo shaping science policy on stem cells, CRISPR, and more. Learn about science policy's real-life impact, her experience at the science policy table, and how science policy can inspire techno optimism. Delve into ethical debates, HIV prevention research, challenges in biotechnology, and the importance of public involvement in scientific discussions.
Alta Charo's role in shaping stem cell policy was inspired by personal experiences and contributed to stabilizing scientific fields and federal funding rules.
Charo's ethical oversight in HIV research emphasized the importance of balancing risks and benefits, ensuring integrity and positive impact in sensitive research areas.
Deep dives
Alta Charo's Background and Role in Science Policy
Alta Charo, a prominent figure in science policy, brings her legal and bioethics expertise to shaping policy on cutting-edge technologies like stem cells, CRISPR, and chimeras. She has served on various advisory boards, including President Obama's Transition Team, with a focus on bioethics, stem cell policy, and reproductive health. Charo's extensive experience includes co-chairing committees for establishing guidelines in areas like embryonic stem cells, contributing to stabilizing scientific fields and shaping federal funding rules.
Impacts of Stem Cells and Regenerative Medicine
Charo's involvement in stem cell and regenerative medicine policy was deeply personal, driven by caring for a friend with ALS. Her work intertwined diverse experiences in human reproduction policy, in vitro fertilization, and bioethics debates. Co-chairing the National Academy's Committee on embryonic stem cell guidelines, she contributed to developing comprehensive guidelines that influenced federal funding policies, ensuring stabilization and progress in the field.
Ethical Challenges in HIV Research
Charo navigated ethical dilemmas in HIV research, particularly in maternal-to-child transmission prevention trials in resource-limited settings. Facing scrutiny and threats to funding, she rigorously evaluated the research ethics to ensure its integrity and positive impact. Her role in reconciling ethical standards with practical implementation underscored the importance of ethical oversight in sensitive research areas.
Navigating Controversial Technologies like Genome Editing
Engaging in complex policy discussions, Charo addressed controversial issues like genome editing and its implications. By co-chairing committees focused on ethical considerations in cutting-edge technologies, she played a crucial role in establishing regulatory frameworks. Her approach emphasized balancing risks and benefits, navigating uncertainties, and triggering global regulatory responses to emerging biotechnologies.
A lawyer and bioethicist by training, Alta Charo has decades of experience in helping to formulate and inform science policy on new and emerging technologies, including stem cells, cloning, CRISPR, and chimeras. The Warren P. Knowles Professor Emerita of Law and Bioethics at the University of Wisconsin at Madison, she served on President Clinton’s National Bioethics Advisory Commission, was a member of President Obama’s transition team, was an advisor for the Food and Drug Administration, and served on more than a dozen study committees for the National Academies of Sciences, Engineering, and Medicine.
In the fourth episode of our Science Policy IRL series, Alta joins Issues contributing editor Molly Galvin to explore how science policy can and does impact people’s lives in real and profound ways. She also describes what it’s like to be one of the only non-scientists at the science policy table, how helping a close friend who died of ALS continues to inspire her work, and why science policy can help us become techno optimists.
Is there something about science policy you’d like us to explore? Let us know by emailing us at podcast@issues.org, or by tagging us on social media with the hashtag #SciencePolicyIRL.