Big Technology Podcast Programming The Code of Life With CRISPR — With Trevor Martin, CEO of Mammoth Biosciences
Feb 16, 2022
Trevor Martin, the CEO and co-founder of Mammoth Biosciences, shares insights on CRISPR technology, revolutionizing gene editing today rather than in a distant future. He discusses its potential to treat genetic diseases and the ethical implications of editing genes, especially concerning enhancing human capabilities. The conversation also dives into the accessibility challenges of biotechnology and the importance of societal consensus on genetic advancements, highlighting how these developments could reshape health outcomes and ethical boundaries in society.
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CRISPR's origins and programmability
- CRISPR proteins are programmable, similar to computers, targeting DNA/RNA sequences.
- They originated in bacteria as an immune defense against viruses.
Gene Editing for Disease
- Gene editing offers potential cures for genetic diseases by modifying DNA.
- Sickle cell disease, caused by misshapen blood cells, is one example.
CRISPR's Mechanism
- CRISPR can target specific genes and cut DNA/RNA with "molecular scissors".
- This allows for gene knockout or insertion of new sequences, potentially curing diseases.