The Curbsiders Internal Medicine Podcast Random Pearls #IM2019 Day 2
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Apr 19, 2019 Discover the latest in medical innovation, like baloxavir, a game-changing flu treatment with its single-dose convenience. Unpack important insights about penicillin allergies and their treatment implications. Learn about non-invasive coronary assessment using supercomputers, which could reshape cardiac practices. Dive into the latest strategies for stress testing and managing syncope, comparing guidelines from the UK and the US. Plus, enjoy lighthearted banter on hiring challenges in academia amidst serious medical discussions!
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New Flu Drug Baloxavir
- Baloxavir is a new flu antiviral that works with a novel mechanism and requires only a single dose.
- It's more expensive than oseltamivir but might become more common due to resistance issues with oseltamivir.
Penicillin Allergy Testing Crucial
- Most patients labeled with penicillin allergy are not truly allergic and can safely take penicillins.
- Negative penicillin allergy testing allows safe use of cephalosporins, especially oral ones for distant mild reactions.
Renal Magnesium Wasting from Chemo
- Some chemotherapy drugs cause renal magnesium wasting leading to hypokalemia and profound hypomagnesemia.
- This electrolyte disturbance may underlie syncope or arrhythmia in patients post chemotherapy.