49ers Talk: A San Francisco 49ers Podcast Who will step up for injured Nick Bosa, banged up Mike Evans in 49ers’ Week 3 matchup vs. Cardinals?
Sep 26, 2026
Bonta Hill, Bay Area sports media personality, previews San Francisco’s clash with Arizona alongside injury updates on Nick Bosa and Mike Evans. Kyle Shanahan, the 49ers’ acclaimed head coach, discusses Brock Purdy’s growth, quarterback anticipation, and the impact of Brandon Cooks, Jordan Watkins, and Deebo Samuel. They also examine defensive leadership, Trey McBride, and Arizona’s revamped attack.
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Arizona Can Exploit San Francisco’s Thin Front
- Arizona is more dangerous than its Seattle loss suggested, especially against a depleted San Francisco front.
- Jacoby Brissett’s quick decisions could neutralize pressure and give Arizona’s offense extra time.
Watkins Gets His Chance Behind Evans
- Mike Evans remains vital even if a hip injury limits his snaps.
- Jordan Watkins, Deebo Samuel, George Kittle, Christian McCaffrey, and Brandon Cooks must collectively replace lost receiving depth.
Make Arizona One-Dimensional Early
- Keep the offense efficient and build an early lead to make Arizona one-dimensional.
- Sustain long drives, run effectively, and protect the injured defense from excessive snaps.